Übersichtsarbeiten - OUP 12/2017

Stellenwert der Histopathologie in der Diagnostik von muskuloskelettalen und periimplantären Gelenkinfektionen*

Interessenkonflikt: Ungeachtet eines möglichen Interessenkonflikts ist dieser wissenschaftliche Beitrag unabhängig und produktneutral. Der Inhalt dieser Veröffentlichung beinhaltet keine Versuche an Menschen und Tieren.

Korrespondenzadresse

Prof. Dr. med. Veit Krenn

Zentrum für Histologie, Zytologie
und Molekulare Diagnostik

Max-Planck-Straße 5

54296 Trier

krenn@patho-trier.de

Literatur

1. Arazna M, Pruchniak MP, Zycinska K, Demkow U: Neutrophil extracellular trap in human diseases. Adv Exp Med Biol. 2013; 756: 1–8

2. Banit DM, Kaufer H, Hartford JM: Intraoperative frozen section analysis in revision total joint arthroplasty. Clin Orthop Relat Res 2002; 401: 230–8

3. Bauer TW, Parvizi J, Kobayashi N, Krebs V: Diagnosis of periprosthetic infection. J Bone Joint Surg Am. 2006; 88: 869–82

4. Ermert D, Zychlinsky A, Urban C: Fungal and bacterial killing by neutrophils. Methods Mol Biol. 2009; 470: 293–312

5. Fink B, Makowiak C, Fuerst M, Berger I et al.: The value of synovial biopsy, joint aspiration and C-reactive protein in the diagnosis of late periprostethic infection of total knee replacements. J. Bone Joint Surg Br. 2008; 90: 874–8

6. Gontarewicz A1, Niggemeyer O, Tharun L, Grancicova L et al.: Morphological study of synovial changes in two-stage reconstructions of the infected hip and knee arthroplasties. BMJ 2012 Open. pii: e001467. doi: 10.1136/ bmjopen-2012–001467

7. Illgner U, Krenn V, Osada N, Bause L.: Histopathology and microbiology of joint infections: extension of diagnostic safety in patients with chronic polyarthritis. Z Rheumatol. 2013; 72: 709–13

8. Krenn VT, Liebisch M, Kölbel B et al.: CD15 focus score: Infection diagnosis and stratification into low-virulence and high-virulence microbial pathogens in periprosthetic joint infection. Pathol Res Pract 2017; 213: 541–47

9. Krenn V, Morawietz L, König A, Haeupl T: [Differential diagnosis of chronic synovitis]. Pathologe 2006; 27: 402–8

10. Krenn V, Morawietz L, Perino G, Kienapfel H et al.: Revised histopathological consensus classification of joint implant related pathology. Pathol Res Pract. 2014; 210: 779–86

11. Kriegsmann J, Hopf T, Jacobs D, Arens N et al.: Applications of molecular pathology in the diagnosis of joint infections. Orthopäde 2009; 38: 531–8

12. Lonner JH, Desai P, Dicesare PE, Steiner G, Zuckerman JD: The reliability of analysis of intraoperative frozen sections for identifying active infection during revision hip or knee arthroplasty. J Bone Joint Surg Am 1996; 78: 1553–58

13. Metso L, Mäki M, Tissari P et al.: Efficacy of a novel PCR- and microarray-based method in diagnosis of a prosthetic joint infection. Acta Orthopaedica 2014; 85: 165–70

14. Morawietz L, Tiddens O, Mueller M, Tohtz S et al: Twenty-three neutrophil granulocytes in 10 high-power fields is the best histopathological threshold to differentiate between aseptic and septic endoprosthesis loosening. Histopathology 2009; 54: 847–53

15. Morawietz L, Classen RA, Schröder JH et al.: Proposal for a histopathological consensus classification of the periprosthetic interface membrane. J Clin Pathol. 2006; 59: 591–7

16. Pandey R, Drakoulakis E, Athanasou NA: An assessment of the histological criteria used to diagnose infection in hip revision arthroplasty tissues. J Clin Pathol 1999; 52: 118–23

17. Parvizi J, Gehrke T, Chen AF: Proceedings of the International Consensus on Periprosthetic Joint Infection. Bone Joint J. 2013; 95-B: 1450–2

18. Schmidt HG, Diefenbeck M, Krenn V et al: Classification of haematogenous and post-traumatic osteomyelitis. Z Orthop Unfall. 2014; 152: 334–42

19. Simbolo M, Gottardi M, Corbo V et al: DNA Qualification workflow for next generation sequencing of histopathological samples. PLoS One 2013; 8: e62692

20. Thomas P, Schuh A, Ring J et al.: Orthopedic surgical implants and allergies: joint statement by the implant allergy working group (AK 20) of the DGOOC (German association of orthopedics and orthopedic surgery), DKG (German contact dermatitis research group) and dgaki (German society for allergology and clinical immunology). Orthopäde 2008; 37: 75–88

21. Tiemann A, Hofmann GO, Krukemeyer MG et al.: Histopathological Osteomyelitis Evaluation Score (HOES) – an innovative approach to histopathological diagnostics and scoring of osteomyelitis. GMS Interdiscip Plast Reconstr Surg DGPW; 3: Doc08. doi: 10.3205/iprs000049. eCollection 2014

22. Trampuz A, Perka C, Borens O: Prosthetic joint infection: new developments in diagnosis and treatment. Dtsch Med Wochenschr. 2013; 138:1571–3

23. Zmistowski B, Della Valle C, Bauer TW et al.: Diagnosis of periprosthetic joint infection. J Arthroplasty 2014; 29 (2 Suppl): 77–83

Fussnoten

*Aus der Sektion Knochen- und Weichteilinfektionen der DGOU

1MVZ-Zentrum für Histologie, Zytologie und Molekulare Diagnostik, Trier

2Klinik für Orthopädie und Traumatologie, SRH Zentralklinikum Suhl

3AMEOS Klinikum Seepark, Geestland

SEITE: 1 | 2 | 3 | 4